Temporal Interference Toolbox

A comprehensive toolbox for temporal interference stimulation research, providing end-to-end neuroimaging and simulation capabilities.

Quick Start Workflow

1. Set up your BIDS project directory
   • Organize your data in BIDS format. Place DICOM files in sourcedata/sub-<subject>/T1w/dicom/ (and optionally T2w).
2. Install Docker Desktop
   • Required for running the toolbox environment.
3. Get the Latest Release
   • Download the latest version (2.x.x or newer) from the Releases page. See the Installation for platform-specific instructions. Note: Versions 1.x.x are no longer supported.
4. Pre-process your data
   • Convert DICOM to NIfTI, run FreeSurfer, and create SimNIBS head models using the pre-processing pipeline.
5. Optimize electrode placement
   • Use flex-search (evolutionary) or ex-search (exhaustive) tools to find optimal stimulation parameters.
6. Simulate TI fields
   • Run FEM-based simulations for your selected montages and parameters.
7. Analyze and visualize results
   • Use the analyzer and visualization tools for ROI-based and atlas-based analysis, and to generate figures and reports.